楊俊杰

楊俊杰，教授，碩士生導師。主要從事與精準診療相關的免疫、生物醫學及人體微生物組學研究。

主要學習經歷

山東師范大學，發育生物學專業，博士。

National University of Singapore, Yong Loo Lin School of Medicine，Department of Microbiology & Immunology，山東省公派高級訪問學者。

主要研究方向

生物醫學免疫/微生物組與腫瘤發生，重點研究免疫及微生物組參與疾病發生發展的潛在機制；多組學網絡關聯和拓撲特征分析等。

主要科研成果

主持山東省自然科學基金項目1項，參與山東省重點研發計劃項目1項及山東省重大科技創新工程項目1項。授權國家發明專利3項，國家新型實用專利5項，計算機軟件著作權1項。出版學術專著1部。近五年發表SCI學術論文21篇。

代表性論文發表在mSystems, 2020（Q1，IF : 7. 342）,Pharmacological Research, 2020 (Q1, IF : 10.334),Genomics，Proteomics & Bioinformatics，2019 (Q1, IF : 9.5)，Frontiers in Microbiology，2019 (Q1, IF : 6.064),Frontiers in Oncology，2018 (Q2, IF : 5.738)，Microbiome, 2018 (Q1, IF : 15.5）等。

1) Changying Zhao^#, Zefeng Wei^#,Junjie Yang^#, Jiaming Zhang, Chunna Yu, Aijun Yang, Min Zhang, Lin Zhang, Ye Wang, Xiaofeng Mu, Xueyuan Heng, Huijun Yang, Zhongtao Gai, Xuenan Wang, Lei Zhang^*. Characterization of vaginal microbiome in women with infertility and its potential correlation with hormone stimulation during IVF surgery.mSystems, 2020, 5(4): e00450-20.

2）Ying Wang^#, Ning Li^#,Jun-Jie Yang^#, Dong-Mei Zhao, Bin Chen5, Guo-Qing Zhang, Shuo Chen, Rui-Fang Cao, Han Yu, Chang-Ying Zhao, Lu Zhao, Yong-Sheng Ge, Yi Liu, Le-Hai Zhang, Wei Hu, Lei Zhang^*, Zhong-Tao Gai^*.Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder.Pharmacological Research, 2020, 157:104784.

3)Junjie Yang^#, Jiaming Zhang^#, Changying Zhao^#, Zhongtao Gai, Xiaofeng Mu, Ye Wang, Chunling Zhang, Zhenzhen Su, Lihe Gao, Dequan Zhu, Zhiwen Zuo, Xueyuan Heng^*, Lei Zhang^*. Blood loss leads to increase in relative abundance of opportunistic pathogens in the gut microbiome of rabbits.Current Microbiology, 2020, 77: 415-424.

4）Li Ning^#,Junjie Yang^#, Jiaming Zhang, Cheng Liang, Ying Wang, Bin Chen, Changying Zhao, Jingwen Wang, Guangye Zhang, Dongmei Zhao, Yi Liu, Lehai Zhang, Jun Yang, Guimei Li^*, Zhongtao Gai^*, Lei Zhang^*, Guoping Zhao. Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment.Genomics, Proteomics & Bioinformatics, 2019, 17(1):26-28.

5）Zhen Zhang^#,Junjie Yang^#, Qiang Feng, Bin Chen3, Meihui Li,Cheng Liang, Mingyu Li, Zhihui Li, Qin Xu, Lei Zhang^*, Wantao Chen^*.Compositional and Functional Analysis of the Microbiome in Tissue and Saliva of Oral Squamous Cell Carcinoma.Frontiers in Microbiology, 2019, 10: 1439.

6) Fanghua Zhang^#, Meng Wang^#,Junjie Yang^#, Qian Xu, Cheng Liang, Bin Chen, Jiaming Zhang, Ying Yang, Huiling Wang, Yongfang Shang, Ye Wang, Xiaofeng Mu, Dequan Zhu, Chunling Zhang, Minxiu Yao^*, Lei Zhang^*. Response of gut microbiota in type 2 diabetes to hypoglycemic agents.Endocrine, 2019, 66(3):485-493.

7) Meng Wang^#,Junjie Yang^#, Zhongtao Gai, Shengnan Huo, Jianhua Zhu, Jun Li, Ranran Wang, Sheng Xing, Guosheng Shi, Feng Shi^*, Lei Zhang^*. Comparison between digital PCR and real-time PCR in detection of Salmonella typhimurium in milk.International Journal of Food Microbiology, 2018, 266: 251-256.

8）XueYing Zhang^#, Gansukh Sukhchuluun^#, TingBei Bo^#, QingSheng Chi,JunJie Yang, Bin Chen, Lei Zhang^*,DeHua Wang^*, Huddling remodels gut microbiota to reduce energy requirements in a small mammal species during cold exposure,Microbiome, 2018, 6: 103.

9）Junjie Yang^#, Xiaofeng Mu, Ye Wang, Dequan Zhu, Jiaming Zhang, Cheng Liang, Bin Chen, Jingwen Wang,Changying Zhao, Zhiwen Zuo, Xueyuan Heng^*, Chunling Zhang^*, Lei Zhang^*. Dysbiosis of the salivary microbiome is associated with non-smoking female lung cancer and correlated with immunocytochemistry markers.Frontiers in Oncology, 2018, 8: 520.

10）Shen Meng^#, Bin Chen^#,Junjie Yang^#,Jingwen Wang, Dequan Zhu, Qingsong Meng^*, Lei Zhang^*. Study of Microbiomes in Aseptically Collected Samples of Human Breast Tissue Using Needle Biopsy and the Potential Role of in situ Tissue Microbiomes for Promoting Malignancy.Frontiers in Oncology, 2018, 8:318.